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133 LiquidAiquid calculation method. ) random networks versus, 187 See also Cellular networks Schematic design mode, BioJADE, 24950 Secondary structures, 287 branching complexity, 310 codewords, 303 constraints, 304 exact pairings, 306 RNA, 289 SELEX (Systematic Evolution of Ligands by Exponential Enrichment), 290 Self-assembling protein arrays, 3839 Self-hybridization, 285 defined, 287 introduction, 28689 patterns in DNA sequences, 285 See also Hybridization Sensitivity analysis, 16162 in quantifying robustness, 162 use, 161 Sensor cooperation algorithm, 357, 360 Sequence analysis, 3234 clone set challenges, 32 experimentalreference comparison, 3233 gene identification and, 70 informatics support, 3334 Sequence contig, 20 Sequence hybridization, 285313 biological point of view, 28994 coding-theoretic view, 30113 introduction, 28689 technological point of view, 294301 Sequences estimation with Wiener filtering, 6162 experimental, 3233 identifier, 61 reference, 3233 riboregulator, 235 self-hybridization patterns, 285 structure, Forex market January See also DNA sequencing Sequence trace, 20 Shine-Delgarno sequence, 246 Short-time Fourier transform, 54 Sickle cell anemia, 206 cause, 206 stroke risk, 221 Signal detection, 5974 Signal estimation, 5974 Signaling networks, 75 Signaling pathways, 7475 Signal processing algorithms, 49 in biochemical reaction network analysis, 90 biological, 4994 concepts, 5158 for Forex market January identification, 6971 homomorphic, 6364 for mass spectrometry, 10122 signals, 5154 spectral analysis, 5758 systems, 5457 systems, examples, 75 Signals, 5154 biological, 51 definition for DNA sequencing, 6061 discrete-time, 52 frequency-domain representation, 5254 mathematical functions, 51 multidimensional, 54 PSD, 58 resampling, 1059 time-domain representation, 5152 Signal-to-noise ratio (SNR), 346, 359 fixed, 357 initial average, 356 lowering, 357 starting, 356 Simpsons paradox, 211 Simulations BioJADE, 25457 future, 25859 generation, 25657 RNA-based, 258 Single-node biased random walk, 34647 Single nucleotide polymorphisms (SNPs), 135, 206 dependencies between, 208 efficiency, 216 linking, 212 as markers, 207 mutation determination, Forex market January Singular value decomposition (SVD), 79, 81 applying, 80 in biological system analysis, 83 component analysis with, 87 defined, 79 eigenvalues resulting from, 82 Sliding window, 120 Small interfering RNA (siRNA), 291 Small-scale motifs, 18990 Smoothing, 101 defined, 119 example, 121 Lowess filter, 120 methods, 119 Savitzky and Golay filter, 121 Soft laser desorption ionization (SLDI), 102 Spectral analysis, 5758 Spectrum with estimated baseline subtracted, 112 with identified ion peaks, 122 low-resolution example, 112 mass, 104 noisy and smoothed, 121 plotting, 111 566 A.
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